Application

Research CategorySignaling

Biochem/physiol Actions

Target Sub-Family: CAMK

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Recombinant human MELK (amino acids 1 - 340), containing an N-terminal GST tag

Maternal embryonic leucine zipper kinase (MELK) is a conserved serine/threonine kinase involved in a variety of cellular functions, including proliferation, differentiation and apoptosis. Its levels are elevated in a number of tumour types and it may be a prognosis marker for some cancers.

Product Source: Recombinant protein of the human MELK gene expressed by baculovirus in insect cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Packaging

Also available in 250µg size - call for pricing and availability and reference catalog number 14-909M when ordering the 250µg size

Physical form

Purified using glutathione-agarose

Quality

Routinely evaluated by phosphorylation of KKLNRTLSFAEPG

Storage and Stability

6 months at -70°C